On December 5th, ISO/TC 81 (Pesticide Nomenclature Technical Committee) provisionally approved the common names of two pesticides: amfenamacril (a fungicide developed by Jiangsu Pesticide Research Institute Co., Ltd.) and triflupyroxazin (a herbicide developed by Liaoning Cynda Chemical Co., Ltd.).

Amfenamacril (P)

A novel myosin inhibitor fungicide co-developed by Jiangsu Pesticide Research Institute Co., Ltd. and Zhejiang University. Based on the company’s original fungicide phenamacril, a drug target model was constructed using molecular docking and molecular dynamics simulation technologies. Through extensive structural design, computer-aided virtual screening, directed synthesis, antibacterial activity testing, and efficacy comparison, this ultra-high-efficiency bactericidal compound was identified—its 90% inhibitory activity against Fusarium graminearum is 20 times that of phenamacril.

• Chinese Chemical Name: Ethyl (2Z)-3-amino-2-cyano-3-[4-(ethylmethylamino)phenyl]acrylate
• 2D Chemical Structure:

• 3D Chemical Structure Diagram:

• Molecular Formula: C₁₅H₁₉N₃O₂
• Relative Molecular Mass: 273.236
• CAS Registry Number: 3095661-21-2
• Sponsor: Jiangsu Pesticide Research Institute Co., Ltd.

Triflupyroxazin (P)

A PPO inhibitor and new-generation non-selective herbicide. Target Markets: Non-selective weeding, defoliant, genetically modified (GM) herbicide-resistant crops, and gene-edited herbicide-resistant crops. As a global high-cost-performance non-selective herbicide, it not only controls invasive alien weeds but also exhibits outstanding efficacy against glyphosate and glufosinate-resistant weeds. Aiming for a paraquat-scale market, it will support the future development of integrated GM seed-herbicide solutions.

• Chinese Chemical Name: 3-[7-Fluoro-3,4-dihydro-3-oxo-4-(2-propyn-1-yl)-2H-1,4-benzoxazin-6-yl]-1-methyl-6-(trifluoromethyl)-2,4(1H,3H)-pyrimidinedione
• 2D Chemical Structure:

• 3D Chemical Structure Diagram:

• Molecular Formula: C₁₇H₁₁F₄N₃O₄
• Relative Molecular Mass: 397.284
• CAS Registry Number: 134554-02-2
• Sponsor: Liaoning Cynda Chemical Co., Ltd.